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Differentially mutated subnetworks discovery
PROBLEM: We study the problem of identifying differentially mutated subnetworks of a large gene–gene interaction network, that is, subnetworks that display a significant difference in mutation frequency in two sets of cancer samples. We formally define the associated computational problem and show t...
Autores principales: | Hajkarim, Morteza Chalabi, Upfal, Eli, Vandin, Fabio |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6441493/ https://www.ncbi.nlm.nih.gov/pubmed/30976291 http://dx.doi.org/10.1186/s13015-019-0146-7 |
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