Cargando…

The PI3K and MAPK/p38 pathways control stress granule assembly in a hierarchical manner

All cells and organisms exhibit stress-coping mechanisms to ensure survival. Cytoplasmic protein-RNA assemblies termed stress granules are increasingly recognized to promote cellular survival under stress. Thus, they might represent tumor vulnerabilities that are currently poorly explored. The trans...

Descripción completa

Detalles Bibliográficos
Autores principales:	Heberle, Alexander Martin, Razquin Navas, Patricia, Langelaar-Makkinje, Miriam, Kasack, Katharina, Sadik, Ahmed, Faessler, Erik, Hahn, Udo, Marx-Stoelting, Philip, Opitz, Christiane A, Sers, Christine, Heiland, Ines, Schäuble, Sascha, Thedieck, Kathrin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Life Science Alliance LLC 2019
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6441495/ https://www.ncbi.nlm.nih.gov/pubmed/30923191 http://dx.doi.org/10.26508/lsa.201800257

Ejemplares similares

A systems study reveals concurrent activation of AMPK and mTOR by amino acids
por: Pezze, Piero Dalle, et al.
Publicado: (2016)

The TSC Complex-mTORC1 Axis: From Lysosomes to Stress Granules and Back
por: Rehbein, Ulrike, et al.
Publicado: (2021)

GePI: large-scale text mining, customized retrieval and flexible filtering of gene/protein interactions
por: Faessler, Erik, et al.
Publicado: (2023)

PLK1 (polo like kinase 1) inhibits MTOR complex 1 and promotes autophagy
por: Ruf, Stefanie, et al.
Publicado: (2017)

mTORC1 Crosstalk With Stress Granules in Aging and Age-Related Diseases
por: Cadena Sandoval, Marti, et al.
Publicado: (2021)

Predicting the Physiological Role of Circadian Metabolic Regulation in the Green Alga Chlamydomonas reinhardtii
por: Schäuble, Sascha, et al.
Publicado: (2011)

SBMLmod: a Python-based web application and web service for efficient data integration and model simulation
por: Schäuble, Sascha, et al.
Publicado: (2017)

Endothelial cell senescence is associated with disrupted cell-cell junctions and increased monolayer permeability
por: Krouwer, Vincent J D, et al.
Publicado: (2012)

Partially non-homogeneous dynamic Bayesian networks based on Bayesian regression models with partitioned design matrices
por: Shafiee Kamalabad, Mahdi, et al.
Publicado: (2019)

Finding new edges: systems approaches to MTOR signaling
por: Heberle, Alexander Martin, et al.
Publicado: (2021)

Heptanoate Improves Compensatory Mechanism of Glucose Homeostasis in Mitochondrial Long-Chain Fatty Acid Oxidation Defect
por: Nurjanah, Siti, et al.
Publicado: (2023)

Upregulation of tryptophanyl-tRNA synthethase adapts human cancer cells to nutritional stress caused by tryptophan degradation
por: Adam, Isabell, et al.
Publicado: (2018)

Quantitative Model of Cell Cycle Arrest and Cellular Senescence in Primary Human Fibroblasts
por: Schäuble, Sascha, et al.
Publicado: (2012)

Cardiac PI3K p110α attenuation delays aging and extends lifespan
por: Abdellatif, Mahmoud, et al.
Publicado: (2022)

Terminally Differentiating Eosinophils Express Neutrophil Primary Granule Proteins as well as Eosinophil-specific Granule Proteins in a Temporal Manner
por: Kim, Karam, et al.
Publicado: (2017)

Mixture prioritization and testing: the importance of toxicokinetics
por: Braeuning, Albert, et al.
Publicado: (2021)

Intracellular Trafficking of Guanylate-Binding Proteins Is Regulated by Heterodimerization in a Hierarchical Manner
por: Britzen-Laurent, Nathalie, et al.
Publicado: (2010)

Comparative Assessment of Quantification Methods for Tumor Tissue Phosphoproteomics
por: Zhang, Yang, et al.
Publicado: (2022)

Hypoxia Inducible Factor 1α Inhibits the Expression of Immunosuppressive Tryptophan-2,3-Dioxygenase in Glioblastoma
por: Mohapatra, Soumya R., et al.
Publicado: (2019)

Reverse engineering a hierarchical regulatory network downstream of oncogenic KRAS
por: Stelniec-Klotz, Iwona, et al.
Publicado: (2012)

The Connection of Azole Fungicides with Xeno-Sensing Nuclear Receptors, Drug Metabolism and Hepatotoxicity
por: Marx-Stoelting, Philip, et al.
Publicado: (2020)

The use of NAMs and omics data in risk assessment
por: Miccoli, Andrea, et al.
Publicado: (2022)

Molecular mechanisms of mTOR regulation by stress
por: Heberle, Alexander Martin, et al.
Publicado: (2014)

Oncogenic β-catenin and PIK3CA instruct network states and cancer phenotypes in intestinal organoids
por: Riemer, Pamela, et al.
Publicado: (2017)

Hippocampus, Retrosplenial and Parahippocampal Cortices Encode Multicompartment 3D Space in a Hierarchical Manner
por: Kim, Misun, et al.
Publicado: (2018)

Transcriptome Analysis of the Hierarchical Response of Histone Deacetylase Proteins That Respond in an Antagonistic Manner to Salinity Stress
por: Ueda, Minoru, et al.
Publicado: (2019)

Metformin promotes anticancer activity of NK cells in a p38 MAPK dependent manner
por: Xia, Wenjiao, et al.
Publicado: (2021)

Fibrates Affect Levels of Phosphorylated p38 in Intestinal Cells in a Differentiation-Dependent Manner
por: Cizkova, Katerina, et al.
Publicado: (2023)

Endotoxin promotes neutrophil hierarchical chemotaxis via the p38-membrane receptor pathway
por: Wang, Xu, et al.
Publicado: (2016)

More than additive effects on liver triglyceride accumulation by combinations of steatotic and non-steatotic pesticides in HepaRG cells
por: Lasch, Alexandra, et al.
Publicado: (2021)

Interleukin‐38 suppresses abdominal aortic aneurysm formation in mice by regulating macrophages in an IL1RL2‐p38 pathway‐dependent manner
por: Kurose, Shun, et al.
Publicado: (2023)

Hierarchical Post-transcriptional Regulation of Colicin E2 Expression in Escherichia coli
por: Lechner, Matthias, et al.
Publicado: (2016)

Metabolism-Disrupting Chemicals Affecting the Liver: Screening, Testing, and Molecular Pathway Identification
por: Fritsche, Kristin, et al.
Publicado: (2023)

Cross-species analysis of hepatic cytochrome P450 and transport protein expression
por: Hammer, Helen, et al.
Publicado: (2020)

p38α MAPK regulates proliferation and differentiation of osteoclast progenitors and bone remodeling in an aging-dependent manner
por: Cong, Qian, et al.
Publicado: (2017)

AGO2 localizes to cytokinetic protrusions in a p38-dependent manner and is needed for accurate cell division
por: Pantazopoulou, Vasiliki I., et al.
Publicado: (2021)

The Time Course of JNK and P38 Activation in Cerebellar Granule Neurons Following Glucose Deprivation and BDNF Treatment
por: Vakili Zahir, Niki, et al.
Publicado: (2012)

Effects of Tianxiangdan Granule treatment on atherosclerosis via NF-κB and p38 MAPK signaling pathways
por: Sun, Long-Fei, et al.
Publicado: (2018)

SCD6 induces ribonucleoprotein granule formation in trypanosomes in a translation-independent manner, regulated by its Lsm and RGG domains
por: Krüger, Timothy, et al.
Publicado: (2013)

Distinct IL‐1α‐responsive enhancers promote acute and coordinated changes in chromatin topology in a hierarchical manner
por: Weiterer, Sinah‐Sophia, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_9l776rr991k01q6b3o27rj3eil