Cargando…
Epidermal development requires ninein for spindle orientation and cortical microtubule organization
In mammalian skin, ninein localizes to the centrosomes of progenitor cells and relocates to the cell cortex upon differentiation of keratinocytes, where cortical arrays of microtubules are formed. To examine the function of ninein in skin development, we use epidermis-specific and constitutive ninei...
Autores principales: | Lecland, Nicolas, Hsu, Chiung-Yueh, Chemin, Cécile, Merdes, Andreas, Bierkamp, Christiane |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Life Science Alliance LLC
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6441496/ https://www.ncbi.nlm.nih.gov/pubmed/30923192 http://dx.doi.org/10.26508/lsa.201900373 |
Ejemplares similares
-
Ninein is essential for the maintenance of the cortical progenitor character by anchoring the centrosome to microtubules
por: Shinohara, Hiroshi, et al.
Publicado: (2013) -
PTRN-1 (CAMSAP) and NOCA-2 (NINEIN) are required for microtubule polarity in Caenorhabditis elegans dendrites
por: He, Liu, et al.
Publicado: (2022) -
Centriolar satellites prevent uncontrolled degradation of centrosome proteins: a speculative review
por: Lecland, Nicolas, et al.
Publicado: (2018) -
Ninein is essential for apico-basal microtubule formation and CLIP-170 facilitates its redeployment to non-centrosomal microtubule organizing centres
por: Goldspink, Deborah A., et al.
Publicado: (2017) -
NuMA-microtubule interactions are critical for spindle orientation and the morphogenesis of diverse epidermal structures
por: Seldin, Lindsey, et al.
Publicado: (2016)