MDM2 promotes epithelial–mesenchymal transition through activation of Smad2/3 signaling pathway in lung adenocarcinoma

BACKGROUND: Mouse double minute 2 (MDM2) contributes to cancer metastasis and epithelial–mesenchymal transition (EMT). This study aimed to investigate small mothers against decapentaplegic (Smad) signaling in MDM2-mediated EMT in lung adenocarcinoma (LAC). MATERIALS AND METHODS: Expression patterns...

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Detalles Bibliográficos
Autores principales: Tang, Yong, Xuan, Yiwen, Qiao, Guibin, Ou, Zhu’an, He, Zhe, Zhu, Qihang, Liao, Ming, Yin, Guilin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2019
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6441555/
https://www.ncbi.nlm.nih.gov/pubmed/30988629
http://dx.doi.org/10.2147/OTT.S185076

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6441555/
https://www.ncbi.nlm.nih.gov/pubmed/30988629
http://dx.doi.org/10.2147/OTT.S185076

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