Human Immunodeficiency Virus (HIV) 2 Superinfection in a Patient Receiving Antiretroviral Therapy With Longstanding HIV-1 Viral Load Suppression

Dual human immunodeficiency virus (HIV) 1 and HIV-2 superinfections are rare but challenging. A HIV-1–infected patient receiving effective antiretroviral therapy was investigated for a severe CD4(+) cell count decline. HIV-2 superinfection was diagnosed and genotypic test revealed mutations conferri...

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Detalles Bibliográficos
Autores principales: Ceia, F, Silva-Pinto, A, Carvalho, A C, Piñeiro, C, Soares, J, Serrão, R, Sarmento, A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Brief Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6441564/
https://www.ncbi.nlm.nih.gov/pubmed/30949532
http://dx.doi.org/10.1093/ofid/ofz063
Descripción
Sumario:Dual human immunodeficiency virus (HIV) 1 and HIV-2 superinfections are rare but challenging. A HIV-1–infected patient receiving effective antiretroviral therapy was investigated for a severe CD4(+) cell count decline. HIV-2 superinfection was diagnosed and genotypic test revealed mutations conferring resistance to most drug class, limiting options for treatment.

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