Human Immunodeficiency Virus (HIV) 2 Superinfection in a Patient Receiving Antiretroviral Therapy With Longstanding HIV-1 Viral Load Suppression

Dual human immunodeficiency virus (HIV) 1 and HIV-2 superinfections are rare but challenging. A HIV-1–infected patient receiving effective antiretroviral therapy was investigated for a severe CD4(+) cell count decline. HIV-2 superinfection was diagnosed and genotypic test revealed mutations conferri...

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Detalles Bibliográficos
Autores principales: Ceia, F, Silva-Pinto, A, Carvalho, A C, Piñeiro, C, Soares, J, Serrão, R, Sarmento, A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Brief Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6441564/
https://www.ncbi.nlm.nih.gov/pubmed/30949532
http://dx.doi.org/10.1093/ofid/ofz063
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author Ceia, F
Silva-Pinto, A
Carvalho, A C
Piñeiro, C
Soares, J
Serrão, R
Sarmento, A
author_facet Ceia, F
Silva-Pinto, A
Carvalho, A C
Piñeiro, C
Soares, J
Serrão, R
Sarmento, A
author_sort Ceia, F
collection PubMed
description Dual human immunodeficiency virus (HIV) 1 and HIV-2 superinfections are rare but challenging. A HIV-1–infected patient receiving effective antiretroviral therapy was investigated for a severe CD4(+) cell count decline. HIV-2 superinfection was diagnosed and genotypic test revealed mutations conferring resistance to most drug class, limiting options for treatment.
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spelling pubmed-64415642019-04-04 Human Immunodeficiency Virus (HIV) 2 Superinfection in a Patient Receiving Antiretroviral Therapy With Longstanding HIV-1 Viral Load Suppression Ceia, F Silva-Pinto, A Carvalho, A C Piñeiro, C Soares, J Serrão, R Sarmento, A Open Forum Infect Dis Brief Reports Dual human immunodeficiency virus (HIV) 1 and HIV-2 superinfections are rare but challenging. A HIV-1–infected patient receiving effective antiretroviral therapy was investigated for a severe CD4(+) cell count decline. HIV-2 superinfection was diagnosed and genotypic test revealed mutations conferring resistance to most drug class, limiting options for treatment. Oxford University Press 2019-02-12 /pmc/articles/PMC6441564/ /pubmed/30949532 http://dx.doi.org/10.1093/ofid/ofz063 Text en © The Author(s) 2019. Published by Oxford University Press on behalf of Infectious Diseases Society of America. http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs licence (http://creativecommons.org/licenses/by-nc-nd/4.0/), which permits non-commercial reproduction and distribution of the work, in any medium, provided the original work is not altered or transformed in any way, and that the work is properly cited. For commercial re-use, please contact journals.permissions@oup.com
spellingShingle Brief Reports
Ceia, F
Silva-Pinto, A
Carvalho, A C
Piñeiro, C
Soares, J
Serrão, R
Sarmento, A
Human Immunodeficiency Virus (HIV) 2 Superinfection in a Patient Receiving Antiretroviral Therapy With Longstanding HIV-1 Viral Load Suppression
title Human Immunodeficiency Virus (HIV) 2 Superinfection in a Patient Receiving Antiretroviral Therapy With Longstanding HIV-1 Viral Load Suppression
title_full Human Immunodeficiency Virus (HIV) 2 Superinfection in a Patient Receiving Antiretroviral Therapy With Longstanding HIV-1 Viral Load Suppression
title_fullStr Human Immunodeficiency Virus (HIV) 2 Superinfection in a Patient Receiving Antiretroviral Therapy With Longstanding HIV-1 Viral Load Suppression
title_full_unstemmed Human Immunodeficiency Virus (HIV) 2 Superinfection in a Patient Receiving Antiretroviral Therapy With Longstanding HIV-1 Viral Load Suppression
title_short Human Immunodeficiency Virus (HIV) 2 Superinfection in a Patient Receiving Antiretroviral Therapy With Longstanding HIV-1 Viral Load Suppression
title_sort human immunodeficiency virus (hiv) 2 superinfection in a patient receiving antiretroviral therapy with longstanding hiv-1 viral load suppression
topic Brief Reports
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6441564/
https://www.ncbi.nlm.nih.gov/pubmed/30949532
http://dx.doi.org/10.1093/ofid/ofz063
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