Indigenous Transmission of Mycobacterium africanum in Canada: A Case Series and Cluster Analysis

Mycobacterium africanum is an important cause of human tuberculosis and is found almost exclusively in West Africa. We identified a cluster of patients in Montreal, Canada, with M africanum disease that share identical genotypic signatures by mycobacterial interspersed repetitive unit-variable numbe...

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Autores principales: Chakravarti, Arpita, Soualhine, Hafid, Sharma, Meenu, Rivest, Paul, Poirier, Louise, Lavallée, Christian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Id Case
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6441568/
https://www.ncbi.nlm.nih.gov/pubmed/30949534
http://dx.doi.org/10.1093/ofid/ofz088
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author Chakravarti, Arpita
Soualhine, Hafid
Sharma, Meenu
Rivest, Paul
Poirier, Louise
Lavallée, Christian
author_facet Chakravarti, Arpita
Soualhine, Hafid
Sharma, Meenu
Rivest, Paul
Poirier, Louise
Lavallée, Christian
author_sort Chakravarti, Arpita
collection PubMed
description Mycobacterium africanum is an important cause of human tuberculosis and is found almost exclusively in West Africa. We identified a cluster of patients in Montreal, Canada, with M africanum disease that share identical genotypic signatures by mycobacterial interspersed repetitive unit-variable number tandem repeat (MIRU-VNTR) typing and a putative epidemiological link, thus providing evidence of possible local transmission of M africanum in Montreal over a 10-year period.
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spelling pubmed-64415682019-04-04 Indigenous Transmission of Mycobacterium africanum in Canada: A Case Series and Cluster Analysis Chakravarti, Arpita Soualhine, Hafid Sharma, Meenu Rivest, Paul Poirier, Louise Lavallée, Christian Open Forum Infect Dis Id Case Mycobacterium africanum is an important cause of human tuberculosis and is found almost exclusively in West Africa. We identified a cluster of patients in Montreal, Canada, with M africanum disease that share identical genotypic signatures by mycobacterial interspersed repetitive unit-variable number tandem repeat (MIRU-VNTR) typing and a putative epidemiological link, thus providing evidence of possible local transmission of M africanum in Montreal over a 10-year period. Oxford University Press 2019-03-07 /pmc/articles/PMC6441568/ /pubmed/30949534 http://dx.doi.org/10.1093/ofid/ofz088 Text en © The Author(s) 2019. Published by Oxford University Press on behalf of Infectious Diseases Society of America. http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs licence (http://creativecommons.org/licenses/by-nc-nd/4.0/), which permits non-commercial reproduction and distribution of the work, in any medium, provided the original work is not altered or transformed in any way, and that the work is properly cited. For commercial re-use, please contact journals.permissions@oup.com
spellingShingle Id Case
Chakravarti, Arpita
Soualhine, Hafid
Sharma, Meenu
Rivest, Paul
Poirier, Louise
Lavallée, Christian
Indigenous Transmission of Mycobacterium africanum in Canada: A Case Series and Cluster Analysis
title Indigenous Transmission of Mycobacterium africanum in Canada: A Case Series and Cluster Analysis
title_full Indigenous Transmission of Mycobacterium africanum in Canada: A Case Series and Cluster Analysis
title_fullStr Indigenous Transmission of Mycobacterium africanum in Canada: A Case Series and Cluster Analysis
title_full_unstemmed Indigenous Transmission of Mycobacterium africanum in Canada: A Case Series and Cluster Analysis
title_short Indigenous Transmission of Mycobacterium africanum in Canada: A Case Series and Cluster Analysis
title_sort indigenous transmission of mycobacterium africanum in canada: a case series and cluster analysis
topic Id Case
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6441568/
https://www.ncbi.nlm.nih.gov/pubmed/30949534
http://dx.doi.org/10.1093/ofid/ofz088
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