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Integrated epigenomic profiling reveals endogenous retrovirus reactivation in renal cell carcinoma

BACKGROUND: Transcriptional dysregulation drives cancer formation but the underlying mechanisms are still poorly understood. Renal cell carcinoma (RCC) is the most common malignant kidney tumor which canonically activates the hypoxia-inducible transcription factor (HIF) pathway. Despite intensive st...

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Detalles Bibliográficos
Autores principales:	Siebenthall, Kyle T., Miller, Chris P., Vierstra, Jeff D., Mathieu, Julie, Tretiakova, Maria, Reynolds, Alex, Sandstrom, Richard, Rynes, Eric, Haugen, Eric, Johnson, Audra, Nelson, Jemma, Bates, Daniel, Diegel, Morgan, Dunn, Douglass, Frerker, Mark, Buckley, Michael, Kaul, Rajinder, Zheng, Ying, Himmelfarb, Jonathan, Ruohola-Baker, Hannele, Akilesh, Shreeram
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2019
Materias:	Research paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6441874/ https://www.ncbi.nlm.nih.gov/pubmed/30827930 http://dx.doi.org/10.1016/j.ebiom.2019.01.063

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