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Ursodeoxycholic acid ameliorates hepatic lipid metabolism in LO2 cells by regulating the AKT/mTOR/SREBP-1 signaling pathway

BACKGROUND: Nonalcoholic fatty liver disease (NAFLD), the most common chronic liver disease, can progress into nonalcoholic steatohepatitis (NASH), cirrhosis, and even hepatocellular carcinoma. Bile acids such as ursodeoxycholic acid (UDCA) play an essential role in the pathogenesis of NAFLD by regu...

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Detalles Bibliográficos
Autores principales:	Hu, Jie, Hong, Wei, Yao, Kan-Nan, Zhu, Xiao-Hong, Chen, Zhi-Yun, Ye, Lei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Baishideng Publishing Group Inc 2019
Materias:	Basic Study
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6441910/ https://www.ncbi.nlm.nih.gov/pubmed/30948912 http://dx.doi.org/10.3748/wjg.v25.i12.1492

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