The antitumor activity of CYB-L10, a human topoisomerase IB catalytic inhibitor

DNA topoisomerase IB (TOP1) is a validated target for discovery and development of antitumor agents. Four TOP1 poisons are clinically used for tumor treatment now. In spite of their effectiveness in solid tumors, these camptothecin (CPT) poisons suffer from many shortcomings. Therefore, many investi...

Descripción completa

Detalles Bibliográficos
Autores principales: Yu, Qian, Chen, Yu, Yang, Hui, Zhang, Hong-Li, Agama, Keli, Pommier, Yves, An, Lin-Kun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2019
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6442119/
https://www.ncbi.nlm.nih.gov/pubmed/30907213
http://dx.doi.org/10.1080/14756366.2018.1516651

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6442119/
https://www.ncbi.nlm.nih.gov/pubmed/30907213
http://dx.doi.org/10.1080/14756366.2018.1516651

Ejemplares similares