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Improved discovery of genetic interactions using CRISPRiSeq across multiple environments

Large-scale genetic interaction (GI) screens in yeast have been invaluable for our understanding of molecular systems biology and for characterizing novel gene function. Owing in part to the high costs and long experiment times required, a preponderance of GI data has been generated in a single envi...

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Detalles Bibliográficos
Autores principales: Jaffe, Mia, Dziulko, Adam, Smith, Justin D., St.Onge, Robert P., Levy, Sasha F., Sherlock, Gavin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6442382/
https://www.ncbi.nlm.nih.gov/pubmed/30782640
http://dx.doi.org/10.1101/gr.246603.118