Cargando…
Improved discovery of genetic interactions using CRISPRiSeq across multiple environments
Large-scale genetic interaction (GI) screens in yeast have been invaluable for our understanding of molecular systems biology and for characterizing novel gene function. Owing in part to the high costs and long experiment times required, a preponderance of GI data has been generated in a single envi...
Autores principales: | Jaffe, Mia, Dziulko, Adam, Smith, Justin D., St.Onge, Robert P., Levy, Sasha F., Sherlock, Gavin |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory Press
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6442382/ https://www.ncbi.nlm.nih.gov/pubmed/30782640 http://dx.doi.org/10.1101/gr.246603.118 |
Ejemplares similares
-
iSeq: A New Double-Barcode Method for Detecting Dynamic Genetic Interactions in Yeast
por: Jaffe, Mia, et al.
Publicado: (2016) -
Targeted regulation of transcription in primary cells using CRISPRa and CRISPRi
por: Jensen, Trine I., et al.
Publicado: (2021) -
Forward Chemical Genetics in Yeast for Discovery of Chemical Probes Targeting Metabolism
por: St.Onge, Robert, et al.
Publicado: (2012) -
Diff-seq: A high throughput sequencing-based mismatch detection assay for DNA variant enrichment and discovery
por: Aggeli, Dimitra, et al.
Publicado: (2018) -
A scalable double-barcode sequencing platform for characterization of dynamic protein-protein interactions
por: Schlecht, Ulrich, et al.
Publicado: (2017)