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Remodeling of epigenome and transcriptome landscapes with aging in mice reveals widespread induction of inflammatory responses
Aging is accompanied by the functional decline of tissues. However, a systematic study of epigenomic and transcriptomic changes across tissues during aging is missing. Here, we generated chromatin maps and transcriptomes from four tissues and one cell type from young, middle-aged, and old mice—yield...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Cold Spring Harbor Laboratory Press
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6442391/ https://www.ncbi.nlm.nih.gov/pubmed/30858345 http://dx.doi.org/10.1101/gr.240093.118 |