Cargando…
Predicting response to BET inhibitors using computational modeling: A BEAT AML project study
Despite advances in understanding the molecular pathogenesis of acute myeloid leukaemia (AML), overall survival rates remain low. The ability to predict treatment response based on individual cancer genomics using computational modeling will aid in the development of novel therapeutics and personali...
Autores principales: | Drusbosky, Leylah M., Vidva, Robinson, Gera, Saji, Lakshminarayana, Anjanasree V., Shyamasundar, Vijayashree P., Agrawal, Ashish Kumar, Talawdekar, Anay, Abbasi, Taher, Vali, Shireen, Tognon, Cristina E., Kurtz, Stephen E., Tyner, Jeffrey W., McWeeney, Shannon K., Druker, Brian J., Cogle, Christopher R. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6442457/ https://www.ncbi.nlm.nih.gov/pubmed/30642575 http://dx.doi.org/10.1016/j.leukres.2018.11.010 |
Ejemplares similares
-
Computational Modeling and Treatment Identification in the Myelodysplastic Syndromes
por: Drusbosky, Leylah M., et al.
Publicado: (2017) -
Identification of Lenalidomide Sensitivity and Resistance Mechanisms in Non-Del(5q) Myelodysplastic Syndromes
por: Drusbosky, Leylah M., et al.
Publicado: (2020) -
ERBB2/HER2 mutations are transforming and therapeutically targetable in leukemia
por: Joshi, Sunil K., et al.
Publicado: (2020) -
HitWalker: variant prioritization for personalized functional cancer genomics
por: Bottomly, Daniel, et al.
Publicado: (2013) -
Endothelial cell derived angiocrine support of acute myeloid leukemia targeted by receptor tyrosine kinase inhibition
por: Drusbosky, Leylah, et al.
Publicado: (2015)