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Diurnal Rhythms Spatially and Temporally Organize Autophagy

Circadian rhythms are a hallmark of physiology, but how such daily rhythms organize cellular catabolism is poorly understood. Here, we used proteomics to map daily oscillations in autophagic flux in mouse liver and related these rhythms to proteasome activity. We also explored how systemic inflammat...

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Detalles Bibliográficos
Autores principales: Ryzhikov, Mikhail, Ehlers, Anna, Steinberg, Deborah, Xie, Wenfang, Oberlander, Eitan, Brown, Samuel, Gilmore, Petra E., Townsend, Reid R., Lane, William S., Dolinay, Tamas, Nakahira, Kiichi, Choi, Augustine M.K., Haspel, Jeffrey A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6442472/
https://www.ncbi.nlm.nih.gov/pubmed/30759397
http://dx.doi.org/10.1016/j.celrep.2019.01.072