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Diurnal Rhythms Spatially and Temporally Organize Autophagy
Circadian rhythms are a hallmark of physiology, but how such daily rhythms organize cellular catabolism is poorly understood. Here, we used proteomics to map daily oscillations in autophagic flux in mouse liver and related these rhythms to proteasome activity. We also explored how systemic inflammat...
Autores principales: | Ryzhikov, Mikhail, Ehlers, Anna, Steinberg, Deborah, Xie, Wenfang, Oberlander, Eitan, Brown, Samuel, Gilmore, Petra E., Townsend, Reid R., Lane, William S., Dolinay, Tamas, Nakahira, Kiichi, Choi, Augustine M.K., Haspel, Jeffrey A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6442472/ https://www.ncbi.nlm.nih.gov/pubmed/30759397 http://dx.doi.org/10.1016/j.celrep.2019.01.072 |
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