Neuro-Protective Role of Metformin in Patients with Acute Stroke and Type 2 Diabetes Mellitus via AMPK/Mammalian Target of Rapamycin (mTOR) Signaling Pathway and Oxidative Stress

BACKGROUND: We investigated the effects of metformin on neurological function and oxidative stress in patients with type 2 diabetes mellitus with acute stroke. MATERIAL/METHODS: We randomly assigned 80 acute stroke patients to 2 groups: the metformin combined group and the insulin group. Each group...

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Detalles Bibliográficos
Autores principales: Zhao, Min, Li, Xiao Wan, Chen, De Z., Hao, Fang, Tao, Shu X., Yu, Hai Yan, Cheng, Rui, Liu, Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scientific Literature, Inc. 2019
Materias:
Clinical Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6442495/
https://www.ncbi.nlm.nih.gov/pubmed/30905926
http://dx.doi.org/10.12659/MSM.911250

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6442495/
https://www.ncbi.nlm.nih.gov/pubmed/30905926
http://dx.doi.org/10.12659/MSM.911250

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