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Neuro-Protective Role of Metformin in Patients with Acute Stroke and Type 2 Diabetes Mellitus via AMPK/Mammalian Target of Rapamycin (mTOR) Signaling Pathway and Oxidative Stress
BACKGROUND: We investigated the effects of metformin on neurological function and oxidative stress in patients with type 2 diabetes mellitus with acute stroke. MATERIAL/METHODS: We randomly assigned 80 acute stroke patients to 2 groups: the metformin combined group and the insulin group. Each group...
Autores principales: | Zhao, Min, Li, Xiao Wan, Chen, De Z., Hao, Fang, Tao, Shu X., Yu, Hai Yan, Cheng, Rui, Liu, Hong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
International Scientific Literature, Inc.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6442495/ https://www.ncbi.nlm.nih.gov/pubmed/30905926 http://dx.doi.org/10.12659/MSM.911250 |
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