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Global analysis of methionine oxidation provides a census of folding stabilities for the human proteome

The stability of proteins influences their tendency to aggregate, undergo degradation, or become modified in cells. Despite their significance to understanding protein folding and function, quantitative analyses of thermodynamic stabilities have been mostly limited to soluble proteins in purified sy...

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Detalles Bibliográficos
Autores principales: Walker, Ethan J., Bettinger, John Q., Welle, Kevin A., Hryhorenko, Jennifer R., Ghaemmaghami, Sina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6442572/
https://www.ncbi.nlm.nih.gov/pubmed/30846556
http://dx.doi.org/10.1073/pnas.1819851116