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Global analysis of methionine oxidation provides a census of folding stabilities for the human proteome
The stability of proteins influences their tendency to aggregate, undergo degradation, or become modified in cells. Despite their significance to understanding protein folding and function, quantitative analyses of thermodynamic stabilities have been mostly limited to soluble proteins in purified sy...
Autores principales: | Walker, Ethan J., Bettinger, John Q., Welle, Kevin A., Hryhorenko, Jennifer R., Ghaemmaghami, Sina |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6442572/ https://www.ncbi.nlm.nih.gov/pubmed/30846556 http://dx.doi.org/10.1073/pnas.1819851116 |
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