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A cell type-selective apoptosis-inducing small molecule for the treatment of brain cancer

Glioblastoma multiforme (GBM; grade IV astrocytoma) is the most prevalent and aggressive form of primary brain cancer. A subpopulation of multipotent cells termed GBM cancer stem cells (CSCs) play a critical role in tumor initiation, tumor maintenance, metastasis, drug resistance, and recurrence fol...

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Detalles Bibliográficos
Autores principales:	Lucki, Natasha C., Villa, Genaro R., Vergani, Naja, Bollong, Michael J., Beyer, Brittney A., Lee, Jae Wook, Anglin, Justin L., Spangenberg, Stephan H., Chin, Emily N., Sharma, Amandeep, Johnson, Kevin, Sander, Philipp N., Gordon, Perry, Skirboll, Stephen L., Wurdak, Heiko, Schultz, Peter G., Mischel, Paul S., Lairson, Luke L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	National Academy of Sciences 2019
Materias:	Biological Sciences
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6442583/ https://www.ncbi.nlm.nih.gov/pubmed/30846550 http://dx.doi.org/10.1073/pnas.1816626116

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