Pharmacological modulation of CXCR4 cooperates with BET bromodomain inhibition in diffuse large B-cell lymphoma

Constitutive activation of the chemokine receptor CXCR4 has been associated with tumor progression, invasion, and chemotherapy resistance in different cancer subtypes. Although the CXCR4 pathway has recently been suggested as an adverse prognostic marker in diffuse large B-cell lymphoma, its biologi...

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Detalles Bibliográficos
Autores principales: Recasens-Zorzo, Clara, Cardesa-Salzmann, Teresa, Petazzi, Paolo, Ros-Blanco, Laia, Esteve-Arenys, Anna, Clot, Guillem, Guerrero-Hernández, Martina, Rodríguez, Vanina, Soldini, Davide, Valera, Alexandra, Moros, Alexandra, Climent, Fina, González-Barca, Eva, Mercadal, Santiago, Arenillas, Leonor, Calvo, Xavier, Mate, José Luís, Gutiérrez-García, Gonzalo, Casanova, Isolda, Mangues, Ramón, Sanjuan-Pla, Alejandra, Bueno, Clara, Menéndez, Pablo, Martínez, Antonio, Colomer, Dolors, Tejedor, Roger Estrada, Teixidó, Jordi, Campo, Elias, López-Guillermo, Armando, Borrell, José Ignacio, Colomo, Luis, Pérez-Galán, Patricia, Roué, Gaël
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ferrata Storti Foundation 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6442946/
https://www.ncbi.nlm.nih.gov/pubmed/29954928
http://dx.doi.org/10.3324/haematol.2017.180505

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