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Hemodynamic provocation with acetazolamide shows impaired cerebrovascular reserve in adults with sickle cell disease

Sickle cell disease is characterized by chronic hemolytic anemia and vascular inflammation, which can diminish the vasodilatory capacity of the small resistance arteries, making them less adept at regulating cerebral blood flow. Autoregulation maintains adequate oxygen delivery, but when vasodilatio...

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Detalles Bibliográficos
Autores principales: Václavů, Lena, Meynart, Benoit N., Mutsaerts, Henri J.M.M., Petersen, Esben Thade, Majoie, Charles B.L.M., VanBavel, Ed T., Wood, John C., Nederveen, Aart J., Biemond, Bart J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ferrata Storti Foundation 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6442969/
https://www.ncbi.nlm.nih.gov/pubmed/30523051
http://dx.doi.org/10.3324/haematol.2018.206094

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