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Hemodynamic provocation with acetazolamide shows impaired cerebrovascular reserve in adults with sickle cell disease
Sickle cell disease is characterized by chronic hemolytic anemia and vascular inflammation, which can diminish the vasodilatory capacity of the small resistance arteries, making them less adept at regulating cerebral blood flow. Autoregulation maintains adequate oxygen delivery, but when vasodilatio...
Autores principales: | Václavů, Lena, Meynart, Benoit N., Mutsaerts, Henri J.M.M., Petersen, Esben Thade, Majoie, Charles B.L.M., VanBavel, Ed T., Wood, John C., Nederveen, Aart J., Biemond, Bart J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Ferrata Storti Foundation
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6442969/ https://www.ncbi.nlm.nih.gov/pubmed/30523051 http://dx.doi.org/10.3324/haematol.2018.206094 |
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