Cargando…
In vitro and in vivo evaluation of possible pro-survival activities of PGE2, EGF, TPO and FLT3L on human hematopoiesis
Myelosuppression is a major and frequently dose-limiting side effect of anticancer therapy and is responsible for most treatment-related morbidity and mortality. In addition, repeated cycles of DNA damage and cell death of hematopoietic stem and progenitor cells, followed by compensatory proliferati...
Autores principales: | Demmerath, Eva-Maria, Bohler, Sheila, Kunze, Mirjam, Erlacher, Miriam |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Ferrata Storti Foundation
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6442978/ https://www.ncbi.nlm.nih.gov/pubmed/30442724 http://dx.doi.org/10.3324/haematol.2018.191569 |
Ejemplares similares
-
Inhibition of the anti-apoptotic protein MCL-1 severely suppresses human hematopoiesis
por: Bohler, Sheila, et al.
Publicado: (2020) -
BCL-XL expression is essential for human erythropoiesis and engraftment of hematopoietic stem cells
por: Afreen, Sehar, et al.
Publicado: (2020) -
S252: MODULATING HEMATOPOIESIS: ENGINEERING TPO VARIANTS WITH DISTINCT HEMATOPOIETIC FUNCTION
por: Masoumi, Zahra, et al.
Publicado: (2023) -
Neonatal Platelets: Lower G(12/13) Expression Contributes to Reduced Secretion of Dense Granules
por: Schlagenhauf, Axel, et al.
Publicado: (2022) -
Lnk Inhibits Tpo–mpl Signaling and Tpo-mediated Megakaryocytopoiesis
por: Tong, Wei, et al.
Publicado: (2004)