TIRAP p.R81C is a novel lymphoma risk variant which enhances cell proliferation via NF-κB mediated signaling in B-cells

Diffuse large B-cell lymphoma is the most common malignant lymphoma in adults. By gene-expression profiling, this lymphoma is divided in three cell-of-origin subtypes with distinct molecular and clinical features. Most lymphomas arise sporadically, yet familial clustering is known, suggesting a gene...

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Detalles Bibliográficos
Autores principales: Burkhard, Regula, Keller, Irene, Arambasic, Miroslav, Juskevicius, Darius, Tzankov, Alexandar, Lundberg, Pontus, Bruggmann, Rémy, Dirnhofer, Stephan, Radpour, Ramin, Novak, Urban
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ferrata Storti Foundation 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6442981/
https://www.ncbi.nlm.nih.gov/pubmed/30381301
http://dx.doi.org/10.3324/haematol.2018.201590

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6442981/
https://www.ncbi.nlm.nih.gov/pubmed/30381301
http://dx.doi.org/10.3324/haematol.2018.201590

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