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Aerobic glycolysis fuels platelet activation: small-molecule modulators of platelet metabolism as anti-thrombotic agents
Platelets are critical to arterial thrombosis, which underlies myocardial infarction and stroke. Activated platelets, regardless of the nature of their stimulus, initiate energy-intensive processes that sustain thrombus, while adapting to potential adversities of hypoxia and nutrient deprivation wit...
Autores principales: | Kulkarni, Paresh P., Tiwari, Arundhati, Singh, Nitesh, Gautam, Deepa, Sonkar, Vijay K., Agarwal, Vikas, Dash, Debabrata |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Ferrata Storti Foundation
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6442984/ https://www.ncbi.nlm.nih.gov/pubmed/30381300 http://dx.doi.org/10.3324/haematol.2018.205724 |
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