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Implication of integrin α2β1 in anoikis of SK-Mel-147 human melanoma cells: a non-canonical function of Akt protein kinase

Suppression of anoikis, a kind of apoptosis caused by disruption of contacts between cell and extracellular matrix, is an important prerequisite for cancer cell metastasis. In this communication, we demonstrate that shRNA-mediated depletion of α2 integrin subunit induces anoikis and substantially de...

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Detalles Bibliográficos
Autores principales: Kozlova, Nadezhda I., Morozevich, Galina E., Ushakova, Natalia A., Berman, Albert E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6443001/
https://www.ncbi.nlm.nih.gov/pubmed/30956761
http://dx.doi.org/10.18632/oncotarget.26746

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