Cargando…

Risk factors associated with Richter’s transformation in patients with chronic lymphocytic leukaemia: protocol for a retrospective population-based cohort study

INTRODUCTION: Richter’s transformation (RT) refers to the development of an aggressive lymphoma in patients with chronic lymphocytic leukaemia (CLL) or small lymphocytic lymphoma. Studies have shown that 2–10% of patients with CLL develop RT including diffuse large B-cell lymphoma (DLBCL) and less c...

Descripción completa

Detalles Bibliográficos
Autores principales:	Hleuhel, Mariam Hussein, Ben-Dali, Yasmin, Da Cunha-Bang, Caspar, Brieghel, Christian, Clasen-Linde, Erik, Niemann, Carsten Utoft, Andersen, Michael Asger
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BMJ Publishing Group 2019
Materias:	Haematology (Incl Blood Transfusion)
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6443055/ https://www.ncbi.nlm.nih.gov/pubmed/30833314 http://dx.doi.org/10.1136/bmjopen-2018-023566

Ejemplares similares

Protocol description of the HOVON 141/VISION trial: a prospective, multicentre, randomised phase II trial of ibrutinib plus venetoclax in patients with creatinine clearance ≥30 mL/min who have relapsed or refractory chronic lymphocytic leukaemia (RR-CLL) with or without TP53 aberrations
por: Levin, Mark-David, et al.
Publicado: (2020)

Health care utilisation following childhood acute lymphoblastic leukaemia: a population-based matched cohort study
por: Jensen, Karen Schow, et al.
Publicado: (2021)

National, clinical cohort study of late effects among survivors of acute lymphoblastic leukaemia: the ALL-STAR study protocol
por: Andrés-Jensen, Liv, et al.
Publicado: (2021)

Prognostic significance of KMT2A-PTD in patients with acute myeloid leukaemia: a systematic review and meta-analysis
por: Ye, Wu, et al.
Publicado: (2023)

Rehabilitation during intensive treatment of acute leukaemia including allogenic stem cell transplantation: a qualitative study of patient experiences
por: Jepsen, Lene Østergaard, et al.
Publicado: (2019)

Health-related quality of life in adults treated for paediatric acute lymphoblastic leukaemia: a cross-sectional and longitudinal cohort study
por: Aili, Katarina, et al.
Publicado: (2022)

Are survival and mortality rates associated with recruitment to clinical trials in teenage and young adult patients with acute lymphoblastic leukaemia? A retrospective observational analysis in England
por: Hough, Rachael, et al.
Publicado: (2017)

Health care utilisation preceding relapse or second malignant neoplasm after childhood acute lymphoblastic leukaemia: a population-based matched cohort study
por: Jensen, Karen Schow, et al.
Publicado: (2021)

Protocol for a multicentre randomised controlled trial examining the effects of temporarily pausing Bruton tyrosine kinase inhibitor therapy to coincide with SARS-CoV-2 vaccination and its impact on immune responses in patients with chronic lymphocytic leukaemia
por: Barber, Vicki S, et al.
Publicado: (2023)

Risk and outcome of acute myeloid leukaemia among survivors of primary diffuse large B-cell lymphoma: a retrospective observational study based on SEER database
por: Du, Yu, et al.
Publicado: (2022)

British OsteoNEcrosis Study (BONES) protocol: a prospective cohort study to examine the natural history of osteonecrosis in older children, teenagers and young adults with acute lymphoblastic leukaemia and lymphoblastic lymphoma
por: Amin, Nadia, et al.
Publicado: (2019)

ALL-RIC trial protocol: a comparison of reduced dose total body irradiation (TBI) and cyclophosphamide with fludarabine and melphalan reduced intensity conditioning in adults with acute lymphoblastic leukaemia (ALL) in complete remission
por: Marks, David I, et al.
Publicado: (2023)

Third-generation CD28/4-1BB chimeric antigen receptor T cells for chemotherapy relapsed or refractory acute lymphoblastic leukaemia: a non-randomised, open-label phase I trial protocol
por: Tang, Xiao-Yi, et al.
Publicado: (2016)

Study protocol for a phase II, multicentre, prospective, non-randomised clinical trial to assess the safety and efficacy of infusing allogeneic activated and expanded natural killer cells as consolidation therapy for paediatric acute myeloblastic leukaemia
por: Muñoz Builes, Mario, et al.
Publicado: (2020)

Selumetinib in combination with dexamethasone for the treatment of relapsed/refractory RAS-pathway mutated paediatric and adult acute lymphoblastic leukaemia (SeluDex): study protocol for an international, parallel-group, dose-finding with expansion phase I/II trial
por: Menne, Tobias, et al.
Publicado: (2022)

MUKnine OPTIMUM protocol: a screening study to identify high-risk patients with multiple myeloma suitable for novel treatment approaches combined with a phase II study evaluating optimised combination of biological therapy in newly diagnosed high-risk multiple myeloma and plasma cell leukaemia
por: Brown, Sarah, et al.
Publicado: (2021)

Safety and efficacy of post-haematopoietic cell transplantation maintenance therapy with blinatumomab for relapsed/refractory CD19-positive B-cell acute lymphoblastic leukaemia: protocol for a phase I–II, multicentre, non-blinded, non-controlled trial (JPLSG SCT-ALL-BLIN21)
por: Sakaguchi, Hirotoshi, et al.
Publicado: (2023)

Effects of vaccines in patients with sickle cell disease: a systematic review protocol
por: Wiyeh, Alison Beriliy, et al.
Publicado: (2018)

Treatment of patients with relapsed or refractory CD19+ lymphoid disease with T lymphocytes transduced by RV-SFG.CD19.CD28.4-1BBzeta retroviral vector: a unicentre phase I/II clinical trial protocol
por: Schubert, Maria-Luisa, et al.
Publicado: (2019)

Screening for monoclonal B-lymphocyte expansion in a hospital-based Chinese population with lymphocytosis: an observational cohort study
por: Xu, Jiadai, et al.
Publicado: (2020)

Characteristics of platelet indices, neutrophil-to-lymphocyte ratio and erythrocyte sedimentation rate compared with C reactive protein in patients with cerebral infarction: a retrospective analysis of comparing haematological parameters and C reactive protein
por: Lee, Jong-Han, et al.
Publicado: (2014)

Risk Factors for Alloimmunisation after red blood Cell Transfusions (R-FACT): a case cohort study
por: Zalpuri, Saurabh, et al.
Publicado: (2012)

Patient self-assessment of hospital pain, mood and health-related quality of life in adults with sickle cell disease
por: Anie, Kofi A, et al.
Publicado: (2012)

Assessment of whole body MRI and sestamibi technetium-99m bone marrow scan in prediction of multiple myeloma disease progression and outcome: a prospective comparative study
por: Khalafallah, Alhossain A, et al.
Publicado: (2013)

Stem cell transplantation of matched sibling donors compared with immunosuppressive therapy for acquired severe aplastic anaemia: a Cochrane systematic review
por: Peinemann, Frank, et al.
Publicado: (2014)

Current practice of venous thromboembolism prevention in acute trusts: a qualitative study
por: McFarland, L, et al.
Publicado: (2014)

An audit of anticoagulant management to assess anticoagulant control using decision support software
por: Harper, Paul, et al.
Publicado: (2014)

Randomised controlled trial of weekly chloroquine to re-establish normal erythron iron flux and haemoglobin recovery in postmalarial anaemia
por: Cox, Sharon E, et al.
Publicado: (2013)

Intracranial haemorrhage in thrombocytopenic haematology patients—a nested case–control study: the InCiTe study protocol
por: Estcourt, Lise J, et al.
Publicado: (2014)

HFE gene mutation and oxidative damage biomarkers in patients with myelodysplastic syndromes and its relation to transfusional iron overload: an observational cross-sectional study
por: De Souza, Geane Felix, et al.
Publicado: (2015)

A study protocol for a randomised controlled trial evaluating clinical effects of platelet transfusion products: the Pathogen Reduction Evaluation and Predictive Analytical Rating Score (PREPAReS) trial
por: Ypma, Paula F, et al.
Publicado: (2016)

Validation of the multivariable In-hospital Mortality for PulmonAry embolism using Claims daTa (IMPACT) prediction rule within an all-payer inpatient administrative claims database
por: Coleman, Craig I, et al.
Publicado: (2015)

Use of heparins in patients with cancer: individual participant data meta-analysis of randomised trials study protocol
por: Schünemann, Holger J, et al.
Publicado: (2016)

Protocol for updating a systematic review of randomised controlled trials on the prophylactic use of intravenous immunoglobulin for patients undergoing haematopoietic stem cell transplantation
por: Cowan, Juthaporn, et al.
Publicado: (2015)

Clinical effects of blood donor characteristics in transfusion recipients: protocol of a framework to study the blood donor–recipient continuum
por: Chassé, Michaël, et al.
Publicado: (2015)

Is self-monitoring an effective option for people receiving long-term vitamin K antagonist therapy? A systematic review and economic evaluation
por: Sharma, Pawana, et al.
Publicado: (2015)

Mutation screening for thalassaemia in the Jino ethnic minority population of Yunnan Province, Southwest China
por: Wang, Shiyun, et al.
Publicado: (2015)

Health-related quality of life after pulmonary embolism: a cross-sectional study
por: Tavoly, Mazdak, et al.
Publicado: (2016)

Gender disparities in red blood cell transfusion in elective surgery: a post hoc multicentre cohort study
por: Gombotz, Hans, et al.
Publicado: (2016)

Aneurysmal SubArachnoid Hemorrhage—Red Blood Cell Transfusion And Outcome (SAHaRA): a pilot randomised controlled trial protocol
por: English, Shane W, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_qaus7agiqq41doeabp64bfa5ju