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Hemodynamic forces enhance decidualization via endothelial-derived prostaglandin E2 and prostacyclin in a microfluidic model of the human endometrium

STUDY QUESTION: Does the uterine vasculature play a localized role in promoting stromal cell decidualization in the human endometrium? SUMMARY ANSWER: Our study demonstrated that hemodynamic forces induced secretion of specific endothelial cell-derived prostanoids that enhanced endometrial perivascu...

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Detalles Bibliográficos
Autores principales: Gnecco, Juan S, Ding, Tianbing, Smith, Caroline, Lu, Jacky, Bruner-Tran, Kaylon L, Osteen, Kevin G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6443116/
https://www.ncbi.nlm.nih.gov/pubmed/30789661
http://dx.doi.org/10.1093/humrep/dez003