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Identification of pathways associated with chemosensitivity through network embedding
Basal gene expression levels have been shown to be predictive of cellular response to cytotoxic treatments. However, such analyses do not fully reveal complex genotype- phenotype relationships, which are partly encoded in highly interconnected molecular networks. Biological pathways provide a comple...
Autores principales: | Wang, Sheng, Huang, Edward, Cairns, Junmei, Peng, Jian, Wang, Liewei, Sinha, Saurabh |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6443184/ https://www.ncbi.nlm.nih.gov/pubmed/30893303 http://dx.doi.org/10.1371/journal.pcbi.1006864 |
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