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The pluripotency factor NANOG controls primitive hematopoiesis and directly regulates Tal1

Progenitors of the first hematopoietic cells in the mouse arise in the early embryo from Brachyury‐positive multipotent cells in the posterior‐proximal region of the epiblast, but the mechanisms that specify primitive blood cells are still largely unknown. Pluripotency factors maintain uncommitted c...

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Detalles Bibliográficos
Autores principales: Sainz de Aja, Julio, Menchero, Sergio, Rollan, Isabel, Barral, Antonio, Tiana, Maria, Jawaid, Wajid, Cossio, Itziar, Alvarez, Alba, Carreño‐Tarragona, Gonzalo, Badia‐Careaga, Claudio, Nichols, Jennifer, Göttgens, Berthold, Isern, Joan, Manzanares, Miguel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6443201/
https://www.ncbi.nlm.nih.gov/pubmed/30814124
http://dx.doi.org/10.15252/embj.201899122

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