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Psoralen-loaded lipid-polymer hybrid nanoparticles enhance doxorubicin efficacy in multidrug-resistant HepG2 cells
BACKGROUND: Psoralen (PSO), a major active component of Psoralea corylifolia, has been shown to overcome multidrug resistance in cancer. A drug carrier comprising a lipid-monolayer shell and a biodegradable polymer core for sustained delivery and improved efficacy of drug have exhibited great potent...
Autores principales: | Yuan, Yueling, Cai, Tiange, Callaghan, Richard, Li, Qianwen, Huang, Yinghong, Wang, Bingyue, Huang, Qingqing, Du, Manling, Ma, Qianqian, Chiba, Peter, Cai, Yu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6443224/ https://www.ncbi.nlm.nih.gov/pubmed/30988617 http://dx.doi.org/10.2147/IJN.S189924 |
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