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SNAC-tag for Sequence-specific Chemical Protein Cleavage
Biocompatible chemical protein cleavage methods have been long-sought to replace enzymatic cleavages, but have yet to be realized. Here, we report the development of the SNAC-tag (Sequence-specific Nickel Assisted Cleavage) to achieve sequence-specific chemical protein cleavage under biocompatible c...
Autores principales: | Dang, Bobo, Mravic, Marco, Hu, Hailin, Schmidt, Nathan, Mensa, Bruk, DeGrado, William F. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6443254/ https://www.ncbi.nlm.nih.gov/pubmed/30923372 http://dx.doi.org/10.1038/s41592-019-0357-3 |
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