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High expression of RAD51 promotes DNA damage repair and survival in KRAS-mutant lung cancer cells

RAD51 recombinase plays a critical role in homologous recombination and DNA damage repair. Here we showed that expression of RAD51 is frequently upregulated in lung cancer tumors compared with normal tissues and is associated with poor survival (hazard ratio (HR) = 2, P = 0.0009). Systematic investi...

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Detalles Bibliográficos
Autores principales:	Hu, Jinfang, Zhang, Zhiguo, Zhao, Lei, Li, Li, Zuo, Wei, Han, Lei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Korean Society for Biochemistry and Molecular Biology 2019
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6443323/ https://www.ncbi.nlm.nih.gov/pubmed/30638176 http://dx.doi.org/10.5483/BMBRep.2019.52.2.213

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