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Sirt1 promotes autophagy and inhibits apoptosis to protect cardiomyocytes from hypoxic stress

Sirtuin 1 (Sirt1) exerts its cardioprotective effects in various cardiovascular diseases via multiple cellular activities. However, the therapeutic implications of Sirt1 in hypoxic cardiomyocytes and the underlying mechanisms remain elusive. The present study investigated whether Sirt1 regulates aut...

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Detalles Bibliográficos
Autores principales: Luo, Guiping, Jian, Zhao, Zhu, Yun, Zhu, Yu, Chen, Baicheng, Ma, Ruiyan, Tang, Fuqin, Xiao, Yingbin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6443335/
https://www.ncbi.nlm.nih.gov/pubmed/30864731
http://dx.doi.org/10.3892/ijmm.2019.4125