A Rare Case of Extramedullary Plasmacytoma Presenting as Massive Upper Gastrointestinal Bleeding

Gastrointestinal (GI) involvement by multiple myeloma is a rare entity. Clinical manifestations depend on the site and extent of involvement. GI bleeding, obstruction, and perforation can complicate the disease course. We report a rare case of an extramedullary plasmacytoma ulcerating through the ga...

Descripción completa

Detalles Bibliográficos
Autores principales: Comba, Isin Y, Torres Luna, Nancy E, Cooper, Christopher, W. Crespo, Maria, Carilli, Allison
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2019
Materias:
Internal Medicine
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6443515/
https://www.ncbi.nlm.nih.gov/pubmed/30972272
http://dx.doi.org/10.7759/cureus.3993
_version_ 1783407846721847296
author Comba, Isin Y
Torres Luna, Nancy E
Cooper, Christopher
W. Crespo, Maria
Carilli, Allison
author_facet Comba, Isin Y
Torres Luna, Nancy E
Cooper, Christopher
W. Crespo, Maria
Carilli, Allison
author_sort Comba, Isin Y
collection PubMed
description Gastrointestinal (GI) involvement by multiple myeloma is a rare entity. Clinical manifestations depend on the site and extent of involvement. GI bleeding, obstruction, and perforation can complicate the disease course. We report a rare case of an extramedullary plasmacytoma ulcerating through the gastric mucosa and presenting as a massive upper GI bleed, which was controlled surgically with en-bloc resection of the mass infiltrating the stomach, distal pancreas, and spleen. To our knowledge, this is the first case of immunoglobulin A (IgA) myeloma with multiple GI organ involvement presenting with massive upper GI bleeding.
format Online
Article
Text
id pubmed-6443515
institution National Center for Biotechnology Information
language English
publishDate 2019
publisher Cureus
record_format MEDLINE/PubMed
spelling pubmed-64435152019-04-10 A Rare Case of Extramedullary Plasmacytoma Presenting as Massive Upper Gastrointestinal Bleeding Comba, Isin Y Torres Luna, Nancy E Cooper, Christopher W. Crespo, Maria Carilli, Allison Cureus Internal Medicine Gastrointestinal (GI) involvement by multiple myeloma is a rare entity. Clinical manifestations depend on the site and extent of involvement. GI bleeding, obstruction, and perforation can complicate the disease course. We report a rare case of an extramedullary plasmacytoma ulcerating through the gastric mucosa and presenting as a massive upper GI bleed, which was controlled surgically with en-bloc resection of the mass infiltrating the stomach, distal pancreas, and spleen. To our knowledge, this is the first case of immunoglobulin A (IgA) myeloma with multiple GI organ involvement presenting with massive upper GI bleeding. Cureus 2019-01-31 /pmc/articles/PMC6443515/ /pubmed/30972272 http://dx.doi.org/10.7759/cureus.3993 Text en Copyright © 2019, Comba et al. http://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Internal Medicine
Comba, Isin Y
Torres Luna, Nancy E
Cooper, Christopher
W. Crespo, Maria
Carilli, Allison
A Rare Case of Extramedullary Plasmacytoma Presenting as Massive Upper Gastrointestinal Bleeding
title A Rare Case of Extramedullary Plasmacytoma Presenting as Massive Upper Gastrointestinal Bleeding
title_full A Rare Case of Extramedullary Plasmacytoma Presenting as Massive Upper Gastrointestinal Bleeding
title_fullStr A Rare Case of Extramedullary Plasmacytoma Presenting as Massive Upper Gastrointestinal Bleeding
title_full_unstemmed A Rare Case of Extramedullary Plasmacytoma Presenting as Massive Upper Gastrointestinal Bleeding
title_short A Rare Case of Extramedullary Plasmacytoma Presenting as Massive Upper Gastrointestinal Bleeding
title_sort rare case of extramedullary plasmacytoma presenting as massive upper gastrointestinal bleeding
topic Internal Medicine
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6443515/
https://www.ncbi.nlm.nih.gov/pubmed/30972272
http://dx.doi.org/10.7759/cureus.3993
work_keys_str_mv AT combaisiny ararecaseofextramedullaryplasmacytomapresentingasmassiveuppergastrointestinalbleeding
AT torreslunanancye ararecaseofextramedullaryplasmacytomapresentingasmassiveuppergastrointestinalbleeding
AT cooperchristopher ararecaseofextramedullaryplasmacytomapresentingasmassiveuppergastrointestinalbleeding
AT wcrespomaria ararecaseofextramedullaryplasmacytomapresentingasmassiveuppergastrointestinalbleeding
AT carilliallison ararecaseofextramedullaryplasmacytomapresentingasmassiveuppergastrointestinalbleeding
AT combaisiny rarecaseofextramedullaryplasmacytomapresentingasmassiveuppergastrointestinalbleeding
AT torreslunanancye rarecaseofextramedullaryplasmacytomapresentingasmassiveuppergastrointestinalbleeding
AT cooperchristopher rarecaseofextramedullaryplasmacytomapresentingasmassiveuppergastrointestinalbleeding
AT wcrespomaria rarecaseofextramedullaryplasmacytomapresentingasmassiveuppergastrointestinalbleeding
AT carilliallison rarecaseofextramedullaryplasmacytomapresentingasmassiveuppergastrointestinalbleeding

Ejemplares similares