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STING-mediated intestinal barrier dysfunction contributes to lethal sepsis

BACKGROUND: Gut integrity is compromised in abdominal sepsis with increased cellular apoptosis and altered barrier permeability. Intestinal epithelial cells (IEC) form a physiochemical barrier that separates the intestinal lumen from the host's internal milieu and is strongly involved in the mu...

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Detalles Bibliográficos
Autores principales:	Hu, Qiongyuan, Ren, Huajian, Li, Guanwei, Wang, Dingyu, Zhou, Quan, Wu, Jie, Zheng, Jiashuo, Huang, Jinjian, Slade, Dominic A., Wu, Xiuwen, Ren, Jianan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2019
Materias:	Research paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6443583/ https://www.ncbi.nlm.nih.gov/pubmed/30878597 http://dx.doi.org/10.1016/j.ebiom.2019.02.055

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