Adeno-associated virus vectored immunoprophylaxis to prevent HIV in healthy adults: a phase 1 randomised controlled trial

BACKGROUND: A preventive vaccine for HIV is a crucial public health need; adeno-associated virus (AAV)-mediated antibody gene delivery could be an alternative to immunisation to induce sustained expression of neutralising antibodies to prevent HIV. We assessed safety and tolerability of rAAV1-PG9DP,...

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Detalles Bibliográficos
Autores principales: Priddy, Frances H, Lewis, David J M, Gelderblom, Huub C, Hassanin, Hana, Streatfield, Claire, LaBranche, Celia, Hare, Jonathan, Cox, Josephine H, Dally, Len, Bendel, Daryl, Montefiori, David, Sayeed, Eddy, Ackland, Jim, Gilmour, Jill, Schnepp, Bruce C, Wright, J Fraser, Johnson, Philip
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier B.V 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6443625/
https://www.ncbi.nlm.nih.gov/pubmed/30885692
http://dx.doi.org/10.1016/S2352-3018(19)30003-7

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