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Increased expression of NAF1 contributes to malignant phenotypes of glioma cells through promoting protein synthesis and associates with poor patient survival

The H/ACA ribonucleoprotein (RNP) complex noncore subunit NAF1 is an indispensable factor during H/ACA RNP maturation, and one of the widely known functions of H/ACA RNP is modulating ribosome biosynthesis. However, the specific biological role and exact mechanism of NAF1 in human cancers including...

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Detalles Bibliográficos
Autores principales: Wei, Jing, Yang, Qi, Shi, Jing, Shi, Bingyin, Ji, Meiju, Hou, Peng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6443650/
https://www.ncbi.nlm.nih.gov/pubmed/30936423
http://dx.doi.org/10.1038/s41389-019-0134-2