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Structural basis for the recognition of K48-linked Ub chain by proteasomal receptor Rpn13

The interaction between K48-linked ubiquitin (Ub) chain and Rpn13 is important for proteasomal degradation of ubiquitinated substrate proteins. Only the complex structure between the N-terminal domain of Rpn13 (Rpn13(NTD)) and Ub monomer has been characterized, while it remains unclear how Rpn13 spe...

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Detalles Bibliográficos
Autores principales:	Liu, Zhu, Dong, Xu, Yi, Hua-Wei, Yang, Ju, Gong, Zhou, Wang, Yi, Liu, Kan, Zhang, Wei-Ping, Tang, Chun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6443662/ https://www.ncbi.nlm.nih.gov/pubmed/30962947 http://dx.doi.org/10.1038/s41421-019-0089-7

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