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HLA-G 3′ untranslated region variants +3187G/G, +3196G/G and +3035T define diametrical clinical status and disease outcome in epithelial ovarian cancer

Expression of the non-classical human leukocyte antigen-G (HLA-G) promotes cancer progression in various malignancies including epithelial ovarian cancer (EOC). As single nucleotide polymorphisms (SNPs) in the HLA-G 3′ untranslated region (UTR) regulate HLA-G expression, we investigated HLA-G 3′UTR...

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Detalles Bibliográficos
Autores principales: Schwich, Esther, Rebmann, Vera, Michita, Rafael Tomoya, Rohn, Hana, Voncken, Jan Willem, Horn, Peter A., Kimmig, Rainer, Kasimir-Bauer, Sabine, Buderath, Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6443684/
https://www.ncbi.nlm.nih.gov/pubmed/30932005
http://dx.doi.org/10.1038/s41598-019-41900-z