NRG1 type I dependent autoparacrine stimulation of Schwann cells in onion bulbs of peripheral neuropathies

In contrast to acute peripheral nerve injury, the molecular response of Schwann cells in chronic neuropathies remains poorly understood. Onion bulb structures are a pathological hallmark of demyelinating neuropathies, but the nature of these formations is unknown. Here, we show that Schwann cells in...

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Detalles Bibliográficos
Autores principales: Fledrich, Robert, Akkermann, Dagmar, Schütza, Vlad, Abdelaal, Tamer A., Hermes, Doris, Schäffner, Erik, Soto-Bernardini, M. Clara, Götze, Tilmann, Klink, Axel, Kusch, Kathrin, Krueger, Martin, Kungl, Theresa, Frydrychowicz, Clara, Möbius, Wiebke, Brück, Wolfgang, Mueller, Wolf C., Bechmann, Ingo, Sereda, Michael W., Schwab, Markus H., Nave, Klaus-Armin, Stassart, Ruth M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6443727/
https://www.ncbi.nlm.nih.gov/pubmed/30931926
http://dx.doi.org/10.1038/s41467-019-09385-6

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