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Identifying Rare Variant Associations in Admixed Populations

An admixed population and its ancestral populations bear different burdens of a complex disease. The ancestral populations may have different haplotypes of deleterious alleles and thus ancestry-gene interaction can influence disease risk in the admixed population. Among admixed individuals, deleteri...

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Detalles Bibliográficos
Autores principales: Qin, Huaizhen, Zhao, Jinying, Zhu, Xiaofeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6443736/
https://www.ncbi.nlm.nih.gov/pubmed/30931973
http://dx.doi.org/10.1038/s41598-019-41845-3