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Neutrophil Effector Functions Are Not Impaired in Duffy Antigen Receptor for Chemokines (DARC)-Null Black South Africans

Neutrophils are well-recognized for their pathogen killing mechanisms and disorders of neutrophil count and function are associated with recurrent infections. The Duffy Antigen Receptor for Chemokines (DARC)-null genotype is predominant in sub-Saharan African ancestry populations and is the major ge...

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Detalles Bibliográficos
Autores principales: Naidoo, Kewreshini K., Ngubane, Ayanda, Gaza, Pedzisai, Moodley, Amber, Ndung'u, Thumbi, Thobakgale, Christina F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6443851/
https://www.ncbi.nlm.nih.gov/pubmed/30972057
http://dx.doi.org/10.3389/fimmu.2019.00551