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GPR139 and Dopamine D2 Receptor Co-express in the Same Cells of the Brain and May Functionally Interact
GPR139, a G(q)-coupled receptor that is activated by the essential amino acids L-tryptophan and L-phenylalanine, is predominantly expressed in the brain and pituitary. The physiological function of GPR139 remains elusive despite the availability of pharmacological tool agonist compounds and knock-ou...
Autores principales: | Wang, Lien, Lee, Grace, Kuei, Chester, Yao, Xiang, Harrington, Anthony, Bonaventure, Pascal, Lovenberg, Timothy W., Liu, Changlu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6443882/ https://www.ncbi.nlm.nih.gov/pubmed/30971885 http://dx.doi.org/10.3389/fnins.2019.00281 |
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