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New Paradigm in the Role of Regulatory T Cells During Pregnancy

Semi-allogenic fetuses are not rejected by the maternal immune system because feto-maternal tolerance induced by CD4(+)CD25(+)FoxP3(+) regulatory T (Treg) cells is established during pregnancy. Paternal antigen-specific Treg cells accumulate during pregnancy, and seminal plasma priming plays an impo...

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Detalles Bibliográficos
Autores principales: Tsuda, Sayaka, Nakashima, Akitoshi, Shima, Tomoko, Saito, Shigeru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6443934/
https://www.ncbi.nlm.nih.gov/pubmed/30972068
http://dx.doi.org/10.3389/fimmu.2019.00573