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A novel optical tracer for VMAT2 applied to live cell measurements of vesicle maturation in cultured human β-cells
The islet β-cells integrate external signals to modulate insulin secretion to better regulate blood glucose levels during periods of changing metabolic demand. The vesicular monoamine transporter type 2 (VMAT2), an important regulator of CNS neurotransmission, has an analogous role in the endocrine...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6443945/ https://www.ncbi.nlm.nih.gov/pubmed/30932004 http://dx.doi.org/10.1038/s41598-019-41891-x |