Nemo-like Kinase Drives Foxp3 Stability and Is Critical for Maintenance of Immune Tolerance by Regulatory T Cells

The Foxp3 transcription factor is a crucial determinant of both regulatory T (T(REG)) cell development and their functional maintenance. Appropriate modulation of tolerogenic immune responses therefore requires the tight regulation of Foxp3 transcriptional output, and this involves both transcriptio...

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Detalles Bibliográficos
Autores principales: Fleskens, Veerle, Minutti, Carlos M., Wu, Xingmei, Wei, Ping, Pals, Cornelieke E.G.M., McCrae, James, Hemmers, Saskia, Groenewold, Vincent, Vos, Harm-Jan, Rudensky, Alexander, Pan, Fan, Li, Huabin, Zaiss, Dietmar M., Coffer, Paul J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6444001/
https://www.ncbi.nlm.nih.gov/pubmed/30917315
http://dx.doi.org/10.1016/j.celrep.2019.02.087

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6444001/
https://www.ncbi.nlm.nih.gov/pubmed/30917315
http://dx.doi.org/10.1016/j.celrep.2019.02.087

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