Nemo-like Kinase Drives Foxp3 Stability and Is Critical for Maintenance of Immune Tolerance by Regulatory T Cells

The Foxp3 transcription factor is a crucial determinant of both regulatory T (T(REG)) cell development and their functional maintenance. Appropriate modulation of tolerogenic immune responses therefore requires the tight regulation of Foxp3 transcriptional output, and this involves both transcriptio...

Descripción completa

Detalles Bibliográficos
Autores principales: Fleskens, Veerle, Minutti, Carlos M., Wu, Xingmei, Wei, Ping, Pals, Cornelieke E.G.M., McCrae, James, Hemmers, Saskia, Groenewold, Vincent, Vos, Harm-Jan, Rudensky, Alexander, Pan, Fan, Li, Huabin, Zaiss, Dietmar M., Coffer, Paul J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6444001/
https://www.ncbi.nlm.nih.gov/pubmed/30917315
http://dx.doi.org/10.1016/j.celrep.2019.02.087

Ejemplares similares

Ejemplares similares