Blockade of miR-3614 maturation by IGF2BP3 increases TRIM25 expression and promotes breast cancer cell proliferation

BACKGROUND: The cross-talk between RNA binding proteins (RBPs) and microRNAs (miRNAs) in the regulation of gene expression is a complex process. Here, we describe a new mode of regulation of TRIM25 expression mediated by an antagonistic interplay between IGF2BP3 and miR-3614-3p. METHODS: The express...

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Detalles Bibliográficos
Autores principales: Wang, Zhenzhen, Tong, Dongdong, Han, Cong, Zhao, Zhenghao, Wang, Xiaofei, Jiang, Ting, Li, Qian, Liu, Siyuan, Chen, Lin, Chen, Yanke, Li, Ang, Huang, Chen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Research paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6444029/
https://www.ncbi.nlm.nih.gov/pubmed/30797711
http://dx.doi.org/10.1016/j.ebiom.2018.12.061

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